The C3 Spacer phosphoramidite can be incorporated internally or at the 5'-end of the oligo. Multiple C3 spacers can be added at either end of an oligo to introduce a long hydrophilic spacer arm for the attachment of fluorophores or other pendent groups.
| Scientific Details |
| MW: |
138.1 |
| Mod Code: |
/5SpC3/ |
| Scientific Details |
| MW: |
138.1 |
| Mod Code: |
/iSpC3/ |
Structure
| Scientific Details |
| MW: |
138.1 |
| Mod Code: |
/3SpC3/ |
Structure
PC (Photo-Cleavable) Spacer can be placed between DNA bases or between the oligo and a 5'-modifier group. It offers a 10-atom spacer arm which can be cleaved with exposure to UV light in the 300-350 nm spectral range. Cleavage releases the oligo with a 5'-phosphate group.
| Scientific Details |
| MW: |
344.3 |
| Mod Code: |
/5SpPC/ |
| Scientific Details |
| MW: |
344.3 |
| Mod Code: |
/iSpPC/ |
Structure
Hexanediol is a six carbon glycol spacer that is capable of blocking extension by DNA polymerases. This 3' modification is capable of supporting synthesis of longer oligos.
| Scientific Details |
| MW: |
180.1 |
| Mod Code: |
/3C6/ |
Structure
Spacer 9 is a triethylene glycol spacer that can be incorporated at the 5'-end or 3'-end of an oligo or internally. Multiple insertions can be used to create long spacer arms.
| Scientific Details |
| MW: |
212.1 |
| Mod Code: |
/5Sp9/ |
| Scientific Details |
| MW: |
212.1 |
| Mod Code: |
/iSp9/ |
| Scientific Details |
| MW: |
212.1 |
| Mod Code: |
/3Sp9/ |
Structure
Spacer 18 is an 18-atom hexa-ethyleneglycol spacer. It is the longest spacer arm that can be added as a single modification.
| Scientific Details |
| MW: |
344.3 |
| Mod Code: |
/5Sp18/ |
| Scientific Details |
| MW: |
344.3 |
| Mod Code: |
/iSp18/ |
| Scientific Details |
| MW: |
344.3 |
| Mod Code: |
/3Sp18/ |
Structure
The 1’,2’-Dideoxyribose modification is used to introduce a stable abasic site within an oligonucleotide.
| Scientific Details |
| MW: |
180.1 |
| Mod Code: |
/5dSp/ |
| Scientific Details |
| MW: |
180.1 |
| Mod Code: |
/idSp/ |
| Scientific Details |
| MW: |
180.1 |
| Mod Code: |
/3dSp/ |
Structure
IDT