Alt-R™ CRISPR Custom Guide RNAs

Guide RNAs for novel Cas enzymes (e.g., prime editing or the Cas13 family)

Our well-established expertise in oligo synthesis combined with an active CRISPR research and development program are what make us a trusted vendor for custom gRNA synthesis.

Fast shipping (usually 3–5 business days)
A range of purification and modification options
Multi-scale delivery in tubes or plates

We also offer a complete selection of Cas9 guide RNAs (sgRNA, crRNA, and tracrRNA) as well as Cas12a guide RNAs.

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CRISPR Custom Guide RNAs

We offer chemically synthesized and modified custom guide RNAs for common as well as exotic research applications. Alt-R Custom Guide RNAs are ideal for prime editing (pegRNA) projects, CRISPR-Cas13 applications, and most alternative CRISPR-Cas systems.

All our CRISPR guide RNAs are available with chemical modifications that increase stability, potency, and/or nuclease resistance. Some modifications can decrease unwanted immune responses in your experiments.

Sequence length range	2 nmol	10 nmol	50 nmol	100 nmol
Guide RNA length 30 – 59 bases
Guide RNA length 60 – 79 bases
Guide RNA length 80 – 109 bases
Guide RNA length 110 – 150 bases

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