Cholesteryl-TEG

3' Cholesteryl-TEG

Cholesterol can be conjugated to oligonucleotides and can facilitate uptake into cells. It has been used as a transfection aid for antisense oligos and siRNAs, both in vitro and in vivo. Cholesterol is a very hydrophobic modification that is best purified using RP-HPLC.
 
 

Structure

Structure
 
 
 
Scientific Details
MW: 756
Mod Code: /3CholTEG/
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