2' Fluoro bases have a fluorine modified ribose which increases binding affinity (Tm) and also confers some relative nuclease resistance when compared to native RNA. These modifications are commonly employed in ribozymes and siRNAs to improve stability in serum or other biological fluids.
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/52FC/ |
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/i2FC/ |
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/32FC/ |
Structure
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/52FU/ |
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/i2FU/ |
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/32FU/ |
Structure
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/52FA/ |
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/i2FA/ |
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/32FA/ |
Structure
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/52FG/ |
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/i2FG/ |
| Scientific Details |
| MW: |
2 |
| Mod Code: |
/32FG/ |
Structure
IDT